Table 1.
KPC-Kp isolates with and without the AME gene aac(6’)-Ib and their aminoglycoside MICs
| Isolate | aac(6’)-Ib genea | KPC gene | Amikacin MIC (mg/L) | Gentamicin MIC (mg/L) | Tobramycin MIC (mg/L) |
|---|---|---|---|---|---|
| NU-CRE193 | no | bla KPC-3 | 1 | 0.25 | 0.5 |
| NU-CRE195 | no | bla KPC-3 | 0.5 | 0.25 | 0.25 |
| NU-CRE236 | no | bla KPC-3 | 2 | 0.5 | 1 |
| NU-CRE055 | yes | bla KPC-3 | 32 | 0.5 | 32 |
| NU-CRE085 | yes | bla KPC-3 | 8 | 0.25 | 8 |
| NU-CRE213 | yes | bla KPC-3 | 8 | 0.25 | 8 |
a
Some isolates co-harboured additional AME genes not predicted to inactivate amikacin, gentamicin or tobramycin as described in Table S3.