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. 2021 Feb 11;7(3):395–402. doi: 10.1001/jamaoncol.2020.7456

Table 2. Number of Positive Test Results and Cancers Detected by MRI, Ultrasonography, and PSA testing.

Variable MRI Ultrasonography PSA (≥3 ng/mL)
Score 3-5 Score 4-5 Score 3-5 Score 4-5
Positive test result 72 43 96 52 40
Biopsy result
Significant cancera 14 11 9 4 7
Insignificant cancerb 7 5 13 7 6
Benign 44 22 63 35 23
Withdrewc 7 5 11 6 4

Abbreviations: MRI, magnetic resonance imaging; PSA, prostate-specific antigen.

SI conversion factor: to convert PSA to micrograms per liter, multiply by 1.

a

Significant cancer is defined as a Gleason score of 3+4 or higher (International Society of Urological Pathology score ≥2) (primary histologic definition of clinical significance).

b

Insignificant cancer is defined as a Gleason score of 3+3 (International Society of Urological Pathology score of 1).

c

The number of men who withdrew after being advised to have a biopsy.