Table 4.

Unadjusted and adjusted linear estimates regressing cognitive measures on sleep measures at follow-up visit 15 (2015–2016) in the SWAN

	RAVLT (immediate)*		RAVLT (delayed)*		SDMT†		DSB†
	β (95% CI)	P-value	β (95% CI)	P-value	β (95% CI)	P-value	β (95% CI)	P-value
TST
Unadjusted	0.02	0.796	0.01	0.896	0.54	0.122	0.13	0.044
	(−0.15, 0.19)		(−0.17, 0.20)		(−0.14, 1.23)		(0.00, 0.27)
Adjusted‡	−0.001	0.993	−0.002	0.984	0.18	0.547	−0.01	0.903
	(−0.16, 0.16)		(−0.18, 0.17)		(−0.41, 0.78)		(−0.13, 0.12)
WASO
Unadjusted	−0.62	0.005	−0.59	0.015	−5.20	<0.001	−0.59	<0.001
	(−1.06, −0.19)		(−1.07, −0.12)		(−6.91, −3.49)		(−0.92, −0.26)
Adjusted‡	−0.28	0.175	−0.11	0.621	−1.85	0.016	−0.09	0.577
	(−0.68, 0.12)		(−0.55, 0.33)		(−3.35, −0.35)		(−0.41, 0.23)
Log SF
Unadjusted	−0.69	0.002	−0.61	0.016	−4.85	<0.001	−0.59	<0.001
	(−1.14, −0.25)		(−1.10, −0.12)		(−6.52, −3.18)		(−0.92, −0.27)
Adjusted‡	−0.39	0.063	−0.19	0.399	−1.99	0.008	−0.15	0.332
	(−0.80, 0.02)		(−0.64, 0.26)		(−3.45, −0.52)		(−0.47, 0.16)

TST, total sleep time; WASO, wake after sleep onset; SF, sleep fragmentation; RAVLT, Rey Auditory Verbal Learning Test; SDMT, Symbol Digit Modalities Test; DSB, Digit Span Backwards.

*N = 687.

^†  N = 1,126.

^‡Adjusted for age, race/ethnicity, site, education, depression, BMI, and number of comorbidities.