Table 5.
Adjusted linear regression estimates between sleep and cognitive measures excluding Hispanic women with interactions between race/ethnicity and sleep at follow-up visit 15 (2015–2016) in the SWAN
| RAVLT (immediate) (N = 687) | RAVLT (delayed) (N = 687) | SDMT (N = 1,078) | DSB (N = 1,078) | |||||
|---|---|---|---|---|---|---|---|---|
| β (95% CI) | P-value | β (95% CI) | P-value | β (95% CI) | P-value | β (95% CI) | P-value | |
| Total sleep model | ||||||||
| Total sleep | 0.04 | 0.767 | −0.12 | 0.406 | 0.33 | 0.488 | −0.18 | 0.073 |
| (−0.22, 0.29) | (−0.39, 0.16) | (−0.60, 1.25) | (−0.38, 0.02) | |||||
| Total sleep * Race/ethnicity | ||||||||
| Total sleep * black | −0.21 | 0.393 | 0.01 | 0.973 | −0.48 | 0.526 | 0.38 | 0.020 |
| (−0.69, 0.27) | (−0.52, 0.54) | (−1.95, 1.00) | (0.06, 0.70) | |||||
| Total sleep * Chinese | −0.01 | 0.963 | 0.27 | 0.235 | 0.76 | 0.414 | 0.28 | 0.162 |
| (−0.42, 0.40) | (−0.18, 0.72) | (−1.06, 2.58) | (−0.11, 0.67) | |||||
| Total sleep * Japanese | −0.03 | 0.904 | 0.23 | 0.338 | 0.18 | 0.854 | 0.29 | 0.169 |
| (−0.46, 0.40) | (−0.24, 0.70) | (−1.73, 2.09) | (−0.12, 0.70) | |||||
| Total sleep * white | reference | reference | reference | reference | ||||
| WASO Model | ||||||||
| WASO | −0.16 | 0.609 | 0.06 | 0.865 | −0.02 | 0.983 | −0.16 | 0.502 |
| (−0.76, 0.45) | (−0.61, 0.72) | (−2.24, 2.19) | (−0.65, 0.32) | |||||
| WASO * Race/ethnicity | ||||||||
| WASO * black | −0.66 | 0.186 | −0.75 | 0.171 | −3.92 | 0.021 | 0.11 | 0.771 |
| (−1.64, 0.32) | (−1.82, 0.32) | (−7.27, −0.58) | (−0.62, 0.83) | |||||
| WASO * Chinese | 0.05 | 0.936 | 0.14 | 0.819 | −4.32 | 0.088 | −0.03 | 0.956 |
| (−1.06, 1.15) | (−1.07, 1.35) | (−9.29, 0.64) | (−1.11, 1.05) | |||||
| WASO * Japanese | 0.47 | 0.508 | 0.04 | 0.955 | 1.76 | 0.590 | 1.04 | 0.141 |
| (−0.92, 1.85) | (−1.47, 1.56) | (−4.64, 8.16) | (−0.35, 2.43) | |||||
| WASO * White | reference | reference | reference | reference | ||||
| Log SF Model | ||||||||
| Log SF | −0.19 | 0.540 | 0.16 | 0.632 | −0.38 | 0.716 | −0.05 | 0.832 |
| (−0.79, 0.41) | (−0.50, 0.82) | (−2.40, 1.65) | (−0.49, 0.39) | |||||
| Log SF * Race/ethnicity | ||||||||
| Log SF * black | −1.03 | 0.063 | −1.49 | 0.015 | −4.90 | 0.004 | −0.40 | 0.289 |
| (−2.13, 0.06) | (−2.68, −0.29) | (−8.27, −1.53) | (−1.13, 0.34) | |||||
| Log SF * Chinese | −0.20 | 0.719 | −0.07 | 0.907 | −3.13 | 0.208 | −0.17 | 0.756 |
| (−1.30, 0.90) | (−1.27, 1.13) | (−8.00, 1.74) | (−1.23, 0.89) | |||||
| Log SF * Japanese | 0.31 | 0.618 | −0.31 | 0.649 | 0.45 | 0.871 | 0.36 | 0.553 |
| (−0.91, 1.53) | (−1.64, 1.02) | (−5.01, 5.91) | (−0.83, 1.55) | |||||
| Log SF * White | Reference | reference | reference | reference | ||||
TST, total sleep time; WASO, wake after sleep onset; SF, sleep fragmentation; RAVLT, Rey Auditory Verbal Learning Test; SDMT, Symbol Digit Modalities Test; DSB, Digit Span Backwards. All models adjusted for age, site, education, depression, BMI, and number of comorbidities.