Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 10;220(3):e202003173. doi: 10.1083/jcb.202003173

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Audano et al.

This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).

PMC Copyright notice

Figure 3. — Zc3h10-mediated F-actin remodeling determines mitochondrial network complexity. (A and C) Left: Representative confocal images of mitochondria detected by the Mitotracker Red CM-H₂XROS probe preadipocytes (36 h). Middle and right: Enlarged images (middle) and relative binary (right) are also shown. Scale bar: 50 µm (left), 10 µm (middle and right). (B and D) Quantitative analysis of mitochondrial networks in preadipocytes (36 h). n = 27 cells in ShZc3h10; n = 28 cells in Zc3h10-Flag; unpaired parametric Student’s t tests; **P < 0.01, ***P < 0.001 vs. Scramble, *P < 0.05 vs. Control vector. (E and F) Colocalization analysis of mitochondria (red) and F-actin (green) in 36-h-differentiated cells. n = 68 cells in ShZc3h10; n = 85 cells in Zc3h10-Flag; unpaired parametric Student’s t test; *P < 0.05 vs. Scramble/Control. Scale bar: 25 µm.