Table 1.

Inclusion and exclusion criteria

Inclusion criteria	Exclusion criteria
Original articles describing the design of a digital application specifically for health contexts (e.g. reducing symptoms, recovering body or cognitive functions, or maintaining health) Use a HMD-VR as the display and interaction technology Describes the VR application as a game Available in the English language Published in peer reviewed academic or professional journals	Only used commercially available HMD-VR games designed for general audiences Opinion or narrative discussions that did not report on the use of a specific VR-based game Grey literature