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. 2021 Jan 29;10:615049. doi: 10.3389/fcimb.2020.615049

Table 3.

Advantages and disadvantages of different prevention and control strategies against Campylobacter in poultry production.

Stage Strategies Advantage Disadvantage
Farm Vaccination Preventive and promising (Annamalai et al., 2013; Neal-McKinney et al., 2014) Expensive, highly specific, and difficult (Saxena et al., 2013; Kaakoush et al., 2015)
Bacteriophages Caused up to 5 log CFU/g reduction of C. jejuni in cecal content of commercial broiler flocks (Kittler et al., 2013) Dilution in the gut over the time and development of resistance (Labrie et al., 2010; Fischer et al., 2013)
Bacteriocins Caused >4 log CFU/g reduction of C. jejuni under in-vitro settings (Svetoch and Stern, 2010) Development of antimicrobial resistance by the multidrug efflux pump CmeABC (Mavri and Smole Možina, 2013)
Probiotics Part of the chicken gut microbiota (Kaakoush et al., 2015) Limited reduction of C. jejuni after 15 d of oral administration (Santini et al., 2010)
Short chain fatty acids Ability to invade the gut epithelium cells (Davidson et al., 2005) Limited reduction of C. jejuni under in-vitro settings (Davidson et al., 2005)