Table 3.
Stage | Strategies | Advantage | Disadvantage |
---|---|---|---|
Farm | Vaccination | Preventive and promising (Annamalai et al., 2013; Neal-McKinney et al., 2014) | Expensive, highly specific, and difficult (Saxena et al., 2013; Kaakoush et al., 2015) |
Bacteriophages | Caused up to 5 log CFU/g reduction of C. jejuni in cecal content of commercial broiler flocks (Kittler et al., 2013) | Dilution in the gut over the time and development of resistance (Labrie et al., 2010; Fischer et al., 2013) | |
Bacteriocins | Caused >4 log CFU/g reduction of C. jejuni under in-vitro settings (Svetoch and Stern, 2010) | Development of antimicrobial resistance by the multidrug efflux pump CmeABC (Mavri and Smole Možina, 2013) | |
Probiotics | Part of the chicken gut microbiota (Kaakoush et al., 2015) | Limited reduction of C. jejuni after 15 d of oral administration (Santini et al., 2010) | |
Short chain fatty acids | Ability to invade the gut epithelium cells (Davidson et al., 2005) | Limited reduction of C. jejuni under in-vitro settings (Davidson et al., 2005) |