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. Author manuscript; available in PMC: 2021 Oct 1.
Published in final edited form as: Adv Healthc Mater. 2020 Sep 2;9(19):e2000796. doi: 10.1002/adhm.202000796

Table 3.

Summary of the potential application tissue systems

Tissue Thickness Current dilemma Where our model can help
Skin 0.3 – 2.5 mm Diffusion limit Modify the CPA loading protocol
Cartilage 1 – 4 mm Diffusion limit Predict the required heating rate
Organ slices 0.25 – 10 mm Balancing toxicity, CPA diffusion, and heating rate Modify the loading protocol therefore decrease the toxicity effect