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. 2021 Feb 10;23(2):e23693. doi: 10.2196/23693

Table 1.

Comparison of models detecting COVID-19 cases, normal cases, and other chest diseases based on medical images (data derived from [22]).

Reference Medical image Disease detected, n Accuracy (%) Methodology Gaps in classification


COVID-19 Normal Other chest diseases


Apostolopoulos and Mpesiana [14] X-ray 224 504 700 93 Used transfer learning on VGG19. MobileNetV2, Inception, Xception, and InceptionResNetV2 Used only 3 classes: COVID-19, pneumonia, and other
Wang et al [23] X-ray 53 8066 5526 92 Introduced COVID-Net—the first open-source COVID-19 detection system Used only 3 classes: COVID-19, pneumonia, and normal
Narin et al [17] X-ray 50 50 N/Aa 98 Used 5 pretrained networks and applied 3 binary classifications for 4 classes of chest x-rays Used only 3 classes: normal, COVID-19, viral and bacterial pneumonia
Brunese et al [22] X-ray 250 3520 2753 97 Defined 2 models based on VGG16: one to classify affected x-ray images from healthy ones and the other to classify COVID-19 from affected x-ray images. Then, they localized the affected areas. Although they used x-ray images of most diseases, they used only 3 classes: COVID-19, healthy, and disease
Song et al [24] CTb 777 708 N/A 86 Proposed DRE-Net and compared its performance with VGG-16, DenseNet, and ResNet Used only 3 classes: COVID-19, bacterial pneumonia, and healthy
Zheng et al [25] CT 313 229 N/A 90 Proposed DeCoVNet for classification Used only 2 classes: COVID-19–positive and COVID-19–negative
Xu et al [26] X-ray 219 175 224 86 Proposed ResNet-18 based CNNc network Used only 3 classes: COVID-19, Influenza-A viral pneumonia, and normal
Ozturk et al [27] X-ray 250 1000 500 92 Proposed DarkCovidNet Used only 3 classes: COVID-19, pneumonia, and no findings
Ardakani et al [28] CT 510 N/A 510 99 Used 10 CNN networks (ie, AlexNet and ResNet-101) for classification of 2 classes Classified COVID-19 class from non–COVID-19 class
Li et al [18] CT 1296 1325 1735 96 Proposed COV-Net for classifying 3 classes Used only 3 classes: COVID-19, community-acquired pneumonia, and non-pneumonia
Abbas et al [15] X-ray 105 80 11 95.12 Proposed DeTrac-ResNet18 CNN that uses Decompose, Transfer, and Compose architecture Used only 3 classes: normal, COVID-19, and SARS
Chen et al [16] CT 51 N/A 55 95.24 Used UNet++ along with Keras for segmentation and COVID-19 detection Used only binary classification for COVID-19 detection

aN/A: not applicable.

bCT: computed tomography.

cCNN: convolutional neural network.