Table 5.
Reference/performance/key performance indicators in in vitro fertilization clinics after resumption of services postlockdown imposed due to COVID-19 pandemic
| Reference/performance/key performance indicators | Values during study period (%) | Historic data (%) | Competency value (Vienna consensus) | Benchmark value (Vienna consensus) |
|---|---|---|---|---|
| Time period | April 2020 - July 2020 | October 2019 - December 2019 | ||
| Number of patients | 52 | 117 | ||
| Reference indicators | - | |||
| Proportion of oocytes recovered | 366/389 (94.1) | 822/875 (93.9) | - | 80%-95% of follicles |
| Proportion of MII oocytes | 265/350 (75.7) | 503/670 (75.1) | - | 75%-90% |
| Performance indicators | ||||
| Postpreparation sperm motility | 90 | 90 | 90% | ≥95% |
| Polyspermy in IVF | 0/15 (0) | 5/152 (3.3) | - | <6% |
| 1 PN in IVF | 0/15 (0) | 6/152 (3.9) | - | <5% |
| 1 PN in ICSI | 3/265 (1.1) | 10/503 (1.9) | - | <3% |
| Good blastocysts | 40/82 (48.8) | 48/107 (44.8) | - | ≥40% |
| Key performance indicators | ||||
| ICSI damage rate | 25/285 (8.8) | 59/503 (11.7) | </=10 | </=5 |
| ICSI - normal fertilization | 187/285 (65.6) | 310/503 (61.6) | ≥65 | ≥80 |
| IVF - normal fertilization | 10/15 (66.7) | 98/152 (64.5) | ≥60 | ≥75 |
| Failed fertilization in IVF | 0 | 0 | <5 | |
| Cleavage rate | 87/93 (93.5) | 328/408 (80.3) | >/=95 | >/=99 |
| Day 2 embryo development rate | 63/93 (67.7) | 228/408 (55.3) | >/=50 | >/=80 |
| Day 3 embryo development rate | 134/197 (68) | 168/408 (41.1) | >/=40 | >/=60 |
| Blastocyst development rate | 73/156 (46.7) | 52/107 (48.5) | >/=40 | >/=60 |
| Implantation rate (day 3) | 2/6 (33.3)* | 18/70 (25.7) | >/=25 | >/=35 |
| Implantation rate (day 5) | 4/6 (66.6)* | 12/25 (48) | >/-35 | >/=60 |
| Blastocyst cryosurvival rate | 25/26 (96.2) | 50/52 (96.1) | >/=90 | /=99 |
| Implantation rate of vitrified and warmed embryos (day 5) | 12/25 (48) | 26/50 (52) | - | - |
*Data are from embryo transfer in fresh IVF/ICSI cycles. Values are expressed as numbers (%). ICSI=Intracytoplasmic sperm injection, IVF=In vitro fertilization, MII=Meiosis II, PN=Pronucleus