Table 3.
Characteristics of infants with postoperative extubation failure compared to infants with successful extubation
| Extubation failure n=5 | Successful extubation n=17 | P | |
|---|---|---|---|
| Age, days | 9 (7-25) | 42 (9-102) | 0.504 |
| Male, n | 3 (60) | 10 (59) | >0.999 |
| Weight, kg | 3.2 (3.1-3.3) | 3.6 (3.2-5.1) | 0.158 |
| BSA, m2 | 0.2 (0.2-0.22) | 0.23 (0.21-0.28) | 0.254 |
| Preexisting ETT, n | 3 (60) | 2 (12) | 0.055 |
| CPB, min | 151±29 | 85±32 | <0.001 |
| DHCA, n | 3 (60) | 4 (24) | 0.274 |
| ECMO, n | 0 (0) | 2 (12) | >0.999 |
| Immediately extubated, n | 0 (0) | 5 (31) | 0.278 |
| Otolaryngology consult, n | 4 (80) | 1 (6) | 0.003 |
| Tracheostomy, n | 1 (20) | 0 (0) | 0.227 |
| CPB ETT CP, cm H2O | 20±1 | 22±3 | 0.206 |
| MAP pre-bypass, mmHg | 49±8 | 54±10 | 0.337 |
| MAP bypass, mmHg | 35±9 | 38±5 | 0.409 |
| MAP post-bypass, mmHg | 57±8 | 58±9 | 0.864 |
| TPP pre-bypass, mmHg | 34±9 | 38±11 | 0.518 |
| TPP bypass, mmHg | 20±9 | 22±6 | 0.697 |
| TPP post-bypass, mmHg | 42±9 | 41±9 | 0.923 |
| CaO2 pre-bypass, mL O2/dL | 17.3±1.4 | 14±3.3 | 0.054 |
| CaO2 bypass, mL O2/dL | 16.6±1.1 | 15.6±1.8 | 0.252 |
| CaO2 post-bypass, mL O2/dL | 14.8±3.5 | 16±1.9 | 0.309 |
Data presented as count with percentage, mean with standard deviation, or median with interquartile range. BSA: Body surface area; CPB: Cardiopulmonary bypass; DHCA: Deep hypothermic circulatory arrest; ECMO: Extracorporeal membrane oxygenation; CPB: Cardiopulmonary bypass; ETT: Endotracheal tube; CP: Cuff pressure; MAP: Mean arterial blood pressure; TPP: Estimated tracheal perfusion pressure; CaO2: Arterial oxygen content