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. 2021 Jan 29;10:566804. doi: 10.3389/fonc.2020.566804

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Copyright © 2021 Chanukuppa, Taware, Taunk, Chatterjee, Sharma, Somasundaram, Rashid, Malakar, Santra and Rapole

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Validation experiments for some of the candidate proteins using ELISA. (A) Concentration ranges of serum albumin in healthy controls (42.80 mg/ml ± 10.13 mg/ml), MM patients (26.45 mg/ml ± 8.14 mg/ml). (B) Concentration ranges of serum apolipoprotein a1 in healthy controls (152.05 mg/dl ± 30.61 mg/dl), MM patients (105.97 mg/dl ± 38.80 mg/dl). (C) Concentration ranges of serum kininogen 1 in healthy controls (139.38 µg/dl ± 28.98 µg/dl), MM patients (173.95 µg/dl ± 26.60 µg/dl), (D) Concentration ranges of serum haptoglobin in healthy controls (110.86 mg/dl ± 30.99 mg/dl), MM patients (145.28 mg/dl ± 45.03 mg/dl). (E) Concentration ranges of serum transferrin in healthy controls (2.64 g/L ± 0.69 g/L), MM patients (1.76 g/L ± 0.48 g/L). Healthy control serum samples (n = 36), MM patients serum samples (n = 36). ****p-value ≤ 0.0001, ***p-value ≤ 0.001.