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. Author manuscript; available in PMC: 2021 Feb 12.
Published in final edited form as: Lancet. 2020 Jan 23;395(10222):450–462. doi: 10.1016/S0140-6736(19)33004-1

Table:

Medications for attention-deficit hyperactivity disorder

Dose range (mg) Delivery
Stimulants

Methylphenidate (short; duration of 4 h)
 Methylphenidate, immediate release 10–60 Tablet
 Methylphenidate, oral solution 10–60 Liquid
 Dexmethylphenidate, immediate release   2·5–20 Tablet
Methylphenidate (intermediate; duration of 6–8 h)
 Methylphenidate hydrochloride, sustained release 10–60 Tablet
 Methylphenidate, long-acting 10–60 Capsule; contents can be sprinkled onto soft food
Methylphenidate (long; duration of 8–12 h)
 Dexmethylphenidate, extended release   5–30 Capsule; contents can be sprinkled onto soft food
 Methylphenidate, oral solution, extended release 20–60 Liquid or chewable tablet
 Methylphenidate, osmotic release 18–54 for children; 18–72 for adults Tablet; osmotic-release oral system
 Methylphenidate, transdermal 10–30 Patch
 Methylphenidate hydrochloride, extended release 10–60 Capsule; contents can be sprinkled onto soft food
Amphetamine (short; duration of action 4–6 h)
 Dextroamphetamine   5–40 Tablet and liquid
 Dextroamphetamine-amphetamine   5–30 Tablet
Amphetamine (long; duration of action 8–12 h)
 Dextroamphetamine-amphetamine, extended release   5–30 Capsule; contents can be sprinkled onto soft food
 Dextroamphetamine, sustained release   5–40 Capsule
 Lisdexamfetamine 10–70 Capsule; contents can be dissolved in liquid

Non-stimulants (duration of action 24 h)

Atomoxetine 0·5–1·4 mg/kg; maximum 100 mg Capsule
Guanfacine, extended release 1–4 Tablet
Clonidine, extended release 0·1–0·4 Tablet