Table 4.

Associated trigger factors for burn-out (demographics, work conditions)

Variable	Univariate HR (CI 95%)	P value	Multivariate initial model HR (CI 95%)	P value	Multivariate final model HR (CI 95%)	P value
Age	0.98 (0.97 to 0.99)	<0.001	0.98 (0.96 to 1.01)	0.173
Children	0.67 (0.52 to 0.87)	0.002	0.78 (0.452 to 1.17)	0.233
Being forced to separate from family	1.30 (0.98 to 1.71)	0.061	1.21 (0.88 to 1.67)	0.232
Resident doctor	1.39 (1.04 to 1.85)	0.026	0.84 (0.53 to 1.32)	0.455
Assisted patients with COVID-19	2.59 (1.49 to 4.50)	0.001	1.61 (0.78 to 3.32)	0.190	2.26 (1.15 to 4.45)	0.017
No access to PPE when needed	1.66 (1.26 to 2.19)	<0.001	1.33 (0.97 to 1.83)	0.075	1.41 (1.05 to 1.91)	0.024
Time to work >1 hour	2.06 (1.21 to 3.53)	0.008	1.75 (0.94 to 3.27)	0.075
Public transport to work	1.62 (1.12 to 2.34)	0.009	1.81 (1.18 to 2.79)	0.007	1.96 (1.30 to 2.95)	0.001
More responsibility at work during pandemic	2.36 (1.73 to 3.21)	<0.001	1.91 (1.32 to 2.78)	0.001	2.13 (1.51 to 3.01)	<0.001
Increase in weekly working hours work	1.56 (1.12 to 2.19)	0.009	1.38 (0.90 to 2.12)	0.136
Economic compensation for overtime	0.42 (0.30 to 0.57)	<0.001	0.42 (0.29 to 0.59)	<0.001	0.43 (0.31 to 0.62)	<0.001
No rest after 24-hour shifts	1.83 (1.27 to 2.63)	0.001	1.33 (0.87 to 2.02)	0.180	1.61 (1.09 to 2.38)	0.016
Not having 48 hours a week to rest	1.66 (1.28 to 2.16)	<0.001	1.21 (0.88 to 1.65)	0.235
No holidays in the last 6 months	1.37 (1.05 to 1.79)	0.019	1.36 (0.99 to 1.86)	0.055	1.36 (1.01 to 1.84)	0.039
Physical or any leisure activity twice a week	0.71 (0.55 to 0.91)	0.008	0.81 (0.60 to 1.09)	0.176
Stable contract	0.72 (0.56 to 0.93)	0.012	1.19 (0.78 to 1.81)	0.406

PPE, personal protective equipment.