Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Feb 11;9(2):e001646. doi: 10.1136/jitc-2020-001646

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See http://creativecommons.org/licenses/by-nc/4.0/.

PMC Copyright notice

m⁶A modification patterns in ccRCC and biological characteristics of m⁶A subtypes. (A) Model-based clustering of ccRCC yields three subtypes in the TCGA-KIRC dataset. C1, cluster1; C2, cluster2; C3, cluster3. (B) Comparison of prognosis among ccRCC subtypes (Kaplan-Meier analysis). (C, D) The heatmap depicted the activation states of biological processes (evaluated by GSVA) among m6Aclusters, and activated and inhibited biological processes were marked with red and green, respectively. (C) m⁶Acluster-C1 vs m6Acluster-C3; (D) m6Acluster-C2 vs m6Acluster-C3. ccRCC, clear cell renal cell carcinoma; GSVA, gene set variation analysis; m⁶A, N6-methyladenosine.