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. 2020 Nov 11;4(5):bjgpopen20X101108. doi: 10.3399/bjgpopen20X101108

Table 5. Clinical effectiveness of topical treatments on psoriasis symptoms.

Key feature of psoriasis Corticosteroid Vitamin D analogue Cal/BD foam fixed-dose combinationa Topical calcineurin inhibitor Salicylic acid Urea Tarb
Redness +++ +/++ +++ +/++c 0 0 +
Scaling + +/++d ++ 0 +++ ++ +
Thickness or infiltration ++ +/++ +++ + 0 0 ++
Itching ++/+++ 0 +++ ++ 0 + ++

Symbols represent clinical effectiveness, where + = somewhat effective and +++ = very effective; 0 represents no or minimal impact on the symptom. This information is based on the expert opinion and clinical experience of the authors and provides a suggested option for a given clinical scenario to contribute to an informed decision; it does not advise that a given treatment is warranted. Only the most commonly used vehicles are included in the Table. It is not intended as a comprehensive list. Clinical effectiveness is based on the active ingredients; overall effectiveness in the real world is also driven by patient adherence and the vehicle plays an important part in patient behaviour. aCal/BD is marketed by LEO Pharma, the sponsor of this work, under the tradenames (UK) Enstilar (Cal/BD foam) and Dovobet (Cal/BD gel and ointment). bUse of tar is country-specific: coal-tar preparations are used in the UK32 and elsewhere as part of the Goeckermann regimen33; however, tar is rarely used in Switzerland, Austria, or Scandinavia. c++ = when used on face. dCream = +; ointment = ++.