Table 1.
Some representative registered clinical trials of MSC therapies
| NCT Number | Title | Phase | Sponsor/Collaborators |
|---|---|---|---|
| NCT02097641 | Human Mesenchymal Stromal Cells For Acute Respiratory Distress Syndrome (START) | Phase 2 |
National Heart, Lung, and Blood Institute (NHLBI) Massachusetts General Hospital Stanford University University of Pittsburgh University of Minnesota Ohio State University University of California, San Francisco |
| NCT00957931 | Allo-HCT MUD for Non-malignant Red Blood Cell (RBC) Disorders: Sickle Cell, Thal, and DBA: Reduced Intensity Conditioning, Co-tx MSCs | Phase 2 |
Stanford University University of Minnesota University of Alabama at Birmingham |
| NCT01771913 | Immunophenotyping of Fresh Stromal Vascular Fraction From Adipose-Derived Stem Cells (ADSC) Enriched Fat Grafts | Phase 2 | University of Sao Paulo |
| NCT01909154 | Safety Study of Local Administration of Autologous Bone Marrow Stromal Cells in Chronic Paraplegia (CME-LEM1) | Phase 1 | Puerta de Hierro University Hospital |
| NCT03102879 | Encapsulated Mesenchymal Stem Cells for Dental Pulp Regeneration |
Phase 1 Phase 2 |
Universidad de los Andes, Chile Cells for Cells, Chile |
| NCT02467387 | A Study to Assess the Effect of Intravenous Dose of (aMBMC) to Subjects With Non-ischemic Heart Failure | N/A |
CardioCell LLC Stemedica Cell Technologies, Inc |
| NCT02387749 | Effect Of Mesenchymal Stem Cells Transfusion on the Diabetic Peripheral Neuropathy Patients | N/A | Cairo University |
| NCT01932164 | Use of Mesenchymal Stem Cells for Alveolar Bone Tissue Engineering for Cleft Lip and Palate Patients | N/A | Hospital Sirio-Libanes |
| NCT02481440 | Repeated Subarachnoid Administrations of hUC-MSCs in Treating SCI |
Phase 1 Phase 2 |
Third Affiliated Hospital, Sun Yat-Sen University, China |
| NCT02165904 | Subarachnoid Administrations of Adults Autologous Mesenchymal Stromal Cells in SCI | Phase 1 | Emory University |
| NCT02330978 | Intravitreal Mesenchymal Stem Cell Transplantation in Advanced Glaucoma | Phase 1 | University of Sao Paulo |
| Treatment of Knee Osteoarthritis With Autologous/ Allogenic Mesenchymal Stem Cells |
Phase 1 Phase 2 |
Red de Terapia Celular Fundacion Teknon, Centro Medico Teknon, Barcelona University of Valladolid |
|
| NCT02037204 | IMPACT: Safety and Feasibility of a Single-stage Procedure for Focal Cartilage Lesions of the Knee |
Phase 1 Phase 2 |
UMC Utrecht |
| NCT02958267 | Investigation of Mesenchymal Stem Cell Therapy for the Treatment of Osteoarthritis of the Knee | Phase 2 | OhioHealth |
| NCT00587990 | Prospective Randomized Study of Mesenchymal Stem Cell Therapy in Patients Undergoing Cardiac Surgery (PROMETHEUS) |
Phase 1 Phase 2 |
National Heart, Lung, and Blood Institute (NHLBI) Johns Hopkins University Specialized Center for Cell Based Therapy The Emmes Company, LLC University of Miami |
| NCT01385644 | A Study to Evaluate the Potential Role of Mesenchymal Stem Cells in the Treatment of Idiopathic Pulmonary Fibrosis | Phase 1 |
The Prince Charles Hospital Mater Medical Research Institute |
| NCT02509156 | Stem Cell Injection in Cancer Survivors | Phase 1 |
The University of Texas Health Science Center, Houston National Heart, Lung, and Blood Institute (NHLBI) |
| NCT02379442 | Early Treatment of Acute Graft Versus Host Disease With Bone Marrow-Derived Mesenchymal Stem Cells and Corticosteroids |
Phase 1 Phase 2 |
National Heart, Lung, and Blood Institute (NHLBI) National Institutes of Health Clinical Center (CC) |
| NCT01087996 | The Percutaneous Stem Cell Injection Delivery Effects on Neomyogenesis Pilot Study (The POSEIDON-Pilot Study) |
Phase 1 Phase 2 |
University of Miami National Heart, Lung, and Blood Institute (NHLBI) The Emmes Company, LLC |
| NCT02013674 | The TRansendocardial Stem Cell Injection Delivery Effects on Neomyogenesis Study (The TRIDENT Study) | Phase 2 |
The Emmes Company, LLC University of Miami |
| NCT01392625 | PercutaneOus StEm Cell Injection Delivery Effects On Neomyogenesis in Dilated CardioMyopathy (The POSEIDON-DCM Study) |
Phase 1 Phase 2 |
National Heart, Lung, and Blood Institute (NHLBI) University of Miami |
| NCT00768066 | The Transendocardial Autologous Cells (hMSC or hBMC) in Ischemic Heart Failure Trial (TAC-HFT) |
Phase 1 Phase 2 |
University of Miami The Emmes Company, LLC |
| NCT00629018 | Safety and Efficacy Study of Stem Cell Transplantation to Treat Dilated Cardiomyopathy | Phase 2 |
University Medical Centre Ljubljana Blood Transfusion Centre of Slovenia Stanford University |
| NCT00927784 | Effect of Intramyocardial Injection of Mesenchymal Precursor Cells on Heart Function in People Receiving an LVAD | Phase 2 |
Icahn School of Medicine at Mount Sinai National Heart, Lung, and Blood Institute (NHLBI) Angioblast Systems |
N/A, not applicable