Skip to main content
. 2020 Nov 16;13(2):1842–1858. doi: 10.18632/aging.103638

Table 2. Univariate and multivariate analyses of clinicopathological factors that correlate with disease-free survival of ccRCC patients.

Clinical variable Univariate analysis Multivariate analysisc
HRa 95% CIb P-value HR 95% CI P-value
Disease Free survival (n=428)
Age (years) 1.377 0.967-1.963 0.076
≤60 (n = 218)
>60 (n = 210)
Gender 1.389 0.939-2.056 0.100
Male (n = 283)
Female (n = 145)
T stage 4.629 3.207-6.681 <0.001
T1 or T2 (n = 286)
T3 or T4 (n = 142)
N stage 5.679 2.85-11.318 <0.001 3.427 1.658-7.080 0.001
N0 or NX (n = 415)
N1 (n = 13)
M stage 8.691 6.00-12.589 <0.001 3.940 2.589-5.996 <0.001
M0 or MX (n = 375)
M1 (n = 53)
G grade 3.481 2.306-5.253 <0.001 2.395 1.565-3.666 <0.001
G1 or G2 (n = 212)
G3 or G4 (n = 216)
Stage 6.671 4.474-9.946 <0.001 3.003 1.880-4.799 <0.001
I or II (n=273)
III or IV (n=155)
DAPK1 0.524 0.386-0.711 <0.001 0.615 0.422-0.896 0.011
Low(n = 214)
High (n = 214)

a HR estimated from Cox proportional hazard regression model; b CI of the estimated HR; c Multivariate models were adjusted for T, N, M, and G grade classification and Stage; CI, confidence interval; HR, hazard ratio; DAPK1, death associated protein kinase 1.