Table 1. Patient characteristics according to sex.
Characteristics | Male | Female | Total | p |
Number (%) | 181 (41.4) | 256 (58.6) | 437 (100.0) | |
Age, mean ± SD, years | 70.1 ± 8.6 | 69.9 ± 9.1 | 69.9 ± 8.9 | 0.802 |
Telomere length, mean ± SD, kbp | 7.85 ± 2.06 | 8.40 ± 2.51 | 8.17 ± 2.35 | 0.015* |
Telomere length, median (IQR), kbp | 7.22 (6.54–8.24) | 7.53 (6.82–9.11) | 7.36 (6.70–8.60) | 0.015* |
Diagnosis, n (%) | 0.003* | |||
N/A | 27 (14.9) | 39 (15.2) | 66 (15.1) | |
Normal | 67 (37.0) | 106 (41.4) | 173 (39.6) | |
MCI | 66 (36.5) | 57 (22.3) | 123 (28.1) | |
AD | 21 (11.6) | 54 (21.1) | 75 (17.2) | |
Amyloid-beta PET, n (%) | 0.069 | |||
N/A | 36 (19.9) | 76 (29.7) | 112 (25.6) | |
Negative | 91 (50.3) | 113 (44.1) | 204 (46.7) | |
Positive | 54 (29.8) | 67 (26.2) | 121 (27.7) | |
Hypertension, n (%) | 0.676 | |||
No | 90 (49.7) | 130 (50.8) | 220 (50.3) | |
Yes | 71 (39.2) | 93 (36.3) | 164 (37.5) | |
Missing | 20 (11.0) | 33 (12.9) | 53 (12.1) | |
Diabetes, n (%) | 0.129 | |||
No | 128 (70.7) | 192 (75.0) | 320 (73.2) | |
Yes | 33 (18.2) | 32 (12.5) | 65 (14.9) | |
Missing | 20 (11.0) | 32 (12.5) | 52 (11.9) | |
Hyperlipidemia, n (%) | 0.427 | |||
No | 110 (60.8) | 161 (62.9) | 271 (62.0) | |
Yes | 50 (27.6) | 61 (23.8) | 111 (25.4) | |
Missing | 21 (11.6) | 34 (13.3) | 55 (12.6) | |
Heart disease, n (%) | 0.499 | |||
No | 142 (78.5) | 203 (79.3) | 345 (78.9) | |
Yes | 19 (10.5) | 21 (8.2) | 40 (9.2) | |
Missing | 20 (11.0) | 32 (12.5) | 52 (11.9) | |
Stroke, n (%) | 0.452 | |||
No | 152 (84.0) | 216 (84.4) | 368 (84.2) | |
Yes | 9 (5.0) | 8 (3.1) | 17 (3.9) | |
Missing | 20 (11.0) | 32 (12.5) | 52 (11.9) |
SD: standard deviation; kbp: kilobase pairs; IQR: interquartile range; N/A: not available; MCI: mild cognitive impairment; AD: Alzheimer’s disease; PET: positron emission tomography. *P<0.05.