Table 3. Multivariable linear regression analysis of telomere lengths among healthy individuals and individuals with MCI and AD according to participant characteristics.
Variable | Multivariable linear regression analysis | |||||
Healthy (n=173) | MCI (n=123) | AD (n=75) | ||||
B (95% CI) | P | B (95% CI) | P | B (95% CI) | P | |
Intercept | 10.872 | 8.999 | 11.835 | |||
Age | -0.042 (-0.087 to 0.002) | 0.063 | -0.015 (-0.051 to 0.021) | 0.414 | -0.060 (-0.102 to -0.018) | 0.006* |
Hypertension | 0.033 (-0.695 to 0.760) | 0.929 | -0.693 (-1.355 to -0.030) | 0.041* | 0.291 (-0.560 to 1.142) | 0.498 |
Diabetes | 0.059 (-1.000 to 1.117) | 0.913 | 0.051 (-0.727 to 0.829) | 0.897 | -0.757 (-2.231 to 0.718) | 0.309 |
Hyperlipidemia | -0.156 (-0.911 to 0.599) | 0.683 | -0.233 (-0.912 to 0.445) | 0.498 | 0.567 (-0.423 to 1.558) | 0.257 |
Heart disease | 1.178 (-0.016 to 2.372) | 0.053 | -0.111 (-1.008 to 0.787) | 0.807 | 1.081 (-0.363 to 2.525) | 0.140 |
Stroke | -1.418 (-3.683 to 0.847) | 0.218 | -0.841 (-2.067 to 0.385) | 0.177 | -0.139 (-1.842 to 1.564) | 0.871 |
MCI: mild cognitive impairment; AD: Alzheimer's disease; CI: confidence interval. *P<0.05.