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. 2021 Jan 16;13(2):3045–3059. doi: 10.18632/aging.202465

Figure 4.

Figure 4

miR-138 inhibition improves results of urodynamic tests in PFD rats after BMSC transplant. (A) miR-138 expression in BMSCs treated with antagomir-NC or miR-138 antagomir evaluated by RT-qPCR; (B) basal bladder pressure level of rats in each group; (C) bladder void volume of rats in each group; (D) bladder void pressure of rats in each group; (E) peak bladder pressure of rats in each group; (F) LPP of rats in each group; (G) the protein expression of IL-1β, elastin, and FBNL5 in rats evaluated by western blot analysis; (H) the content of IL-1β and elastin in peripheral blood of rats examined by ELISA. * p < 0.05 vs. BMSCs treated with antagomir-NC or rats injected with saline (control rats); # p < 0.05 vs. PFD rats injected with BMSCsantagomir-NC; statistical data were measurement data, and described as mean ± standard deviation. The unpaired t test was conducted for comparison between two groups. The one-way ANOVA was adopted for comparison among multiple groups, followed by Tukey’s post hoc test. The experiment was repeated 3 times independently.