Table 1. Blood gas analysis during mechanical ventilation.
| Groups | INITIAL | FINAL | Time effect | Group effect | Interaction | |
|---|---|---|---|---|---|---|
| PaO2/FiO2 (mmHg) | p = 0.003 | p = 0.949 | p = 0.328 | |||
| PSV | 370 ± 35 | 442 ± 70† | ||||
| BIVENTLow-Effort | 386 ± 71 | 422 ± 86 | ||||
| BIVENTHigh-Effort | 382 ± 49 | 408 ± 52 | ||||
| pHa | p = 0.011 | p = 0.439 | p = 0.543 | |||
| PSV | 7.37 ± 0.04 | 7.34 ± 0.03 | ||||
| BIVENTLow-Effort | 7.39 ± 0.02 | 7.35 ± 0.09 | ||||
| BIVENTHigh-Effort | 7.42 ± 0.03 | 7.35 ± 0.06 | ||||
| PaCO2 (mmHg) | p = 0.048 | p = 0.787 | p = 0.674 | |||
| PSV | 39 ± 8 | 46 ± 7 | ||||
| BIVENTLow-Effort | 39 ± 5 | 42 ± 8 | ||||
| BIVENTHigh-Effort | 37 ± 3 | 43 ± 6 | ||||
| HCO3 (mmol/L) | p = 0.734 | p = 0.831 | p = 0.189 | |||
| PSV | 21.9 ± 3.8 | 24.0 ± 2.5 | ||||
| BIVENTLow-Effort | 23.9 ± 3.1 | 22.7 ± 2.1 | ||||
| BIVENTHigh-Effort | 24.5 ± 1.4 | 22.7 ± 1.9 |
Blood gas analysis at INITIAL and FINAL. PSV: pressure-support ventilation with ΔP set to achieve a VT of 6 mL/kg (n = 7); BIVENTLow-Effort: Biphasic positive airway pressure at 50 controlled breaths/min. Animals were allowed to breath either at high and low positive airway pressures, and anesthesia was modulated to keep low inspiratory effort (n = 7). BIVENTHigh-Effort: Biphasic positive airway pressure at 50 controlled breaths/min. Animals were allowed to breath either at high and low positive airway pressures, and anesthesia was modulated to keep high inspiratory effort (n = 7). Values represent mean ± standard deviation (SD). Comparisons were done using a mixed linear model based on a random intercept for each animal followed by Bonferroni’s test was used (p<0.05).
† vs INITIAL (p<0.05).