Fig 1. Apoptosis and hemorrhage/edema in the colon is more prominent in animals infected with WT vs ΔΔstx EHEC.

(A) Apoptotic nuclei in colon sections from infant rabbits inoculated with PBS (mock), WT or ΔΔstx EHEC. Scores for individual animals are plotted with the median (red line). Statistical comparisons were made using a Mann-Whitney U, p<0.05 (*), 0.01 (**), or 0.001 (***). (B-D): Example images from mock (score = 0), WT (score = 4), and ΔΔstx (score = 2) infected colons. White arrows indicate apoptotic nuclei. (E): Severity of hemorrhage/edema. (F-H): Representative example images from mock (score = 0), WT (score = 3) and ΔΔstx (score = 1) infected colons. Scale bars indicate 50 μm. Orange boxes denotes inset.