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. Author manuscript; available in PMC: 2022 Feb 11.

Published in final edited form as: J Med Chem. 2021 Jan 26;64(3):1733–1761. doi: 10.1021/acs.jmedchem.0c02201

Figure 1. — Structures of representative reported hPXR agonists rifampicin (1), dexamethasone (2), solomonsterol A (3) , T0901317 (4), praeruptorin A (5) and antagonists sulforaphane (6), ketoconazole (7), metformin (8), A-792611 (9), and SPA70 (10).

Figure 1. — Structures of representative reported hPXR agonists rifampicin (1), dexamethasone (2), solomonsterol A (3) , T0901317 (4), praeruptorin A (5) and antagonists sulforaphane (6), ketoconazole (7), metformin (8), A-792611 (9), and SPA70 (10).