Figure 5. The effects of As2O3 and baicalin on formamidopyrimidine-DNA glycosylase (FPG)-digestible adducts in human umbilical vein endothelial cells (HUVECs). A: HUVECs were treated with 0-20 μM As2O3 for 24 h and FPG-digestible adducts produced were detected with comet assay. The data are presented as comet moments. B: The effect on FPG-digestible adducts in HUVECs after pretreatment with baicalin for 1 h, and cotreatment of baicalin with 20 μM (◆), 10 μM (▼) or 0 μM (●) As2O3 for 24 h. Data are the mean±SD for three independent experiments. *Significantly different at p<0.05 compared with untreated cells.
