Table 3.

Determinants of white matter infarct volume after endovascular thrombectomy among large vessel occlusion stroke patients. Several variables were associated with greater natural log-transformed white matter infarct volumes in univariable analyses. In a multivariable model including these variables and controlling for total infarct volume (to identify unique determinants of white matter infarct volume), only greater total infarct volume and recanalization-to-MRI time were independently associated with greater white matter infarct volume. Abbreviations: TIA transient ischemic attack, NIHSS NIH Stroke Scale, ICA internal carotid artery, M1 first segment of middle cerebral artery, LKW last known well, TICI Thrombolysis in Cerebral Infarction, MRI magnetic resonance imaging, β beta parameter estimate.

	Univariable		Multivariable
	β	P	β	P
Age, Years	−0.147	0.059	−0.024	0.648
Female	−0.131	0.091	−0.016	0.737
Hypertension	−0.029	0.711
Diabetes	0.100	0.199
Atrial Fibrillation	−0.176	0.023	−0.046	0.377
Stroke/TIA History	−0.060	0.443
Coronary Artery Disease	−0.070	0.366
Smoking	0.020	0.802
Presenting NIHSS	0.037	0.635
Cervical ICA Disease	0.148	0.057	0.086	0.085
ICA Terminus Occlusion	−0.014	0.855
M1 Occlusion	−0.016	0.839
Alteplase	−0.033	0.674
LKW-Alteplase Time, Min	0.158	0.134
LKW-Groin Time, Min	0.156	0.044	0.071	0.137
Groin-Recanalization Time, Min	0.306	<0.0001	0.033	0.530
TICI 2b-3	−0.371	<0.0001	−0.026	0.624
Recanalization-MRI Time, Hr	0.243	0.003	0.119	0.017
Total Infarct Volume, cc	0.826	<0.0001	0.755	<0.0001