Extended Data Fig. 5. ALC1 deficiency results in increased trapping of PARP1 and PARP2 by PARPi upon DNA damage.
a-b Representative images (left) and quantification (right) of PARP1(a) and PARP2 (b) trapping in UWB1.289 cells. Indicated treatments were performed for 4 hours. Median is indicated. p-value determined by Mann-Whitney was derived from n≥107 cells sampled over two biologically independent experiments.