Table 2.
Vascular risk factors at baseline
| Vascular risk factors | NC (N = 84) | MCI (N = 55) | p value |
|---|---|---|---|
| Diabetes (H) | 10 (12.2) | 16 (29.1) | 0.01 |
| Hypercholesterolemia (H) | 26 (31.7) | 20 (36.3) | 0.50 |
| Hypertension (H) | 46 (56.1%) | 40 (72.73) | 0.03 |
| Hypertrigliceridemia (H) | 9 (11.0) | 11 (20.0) | 0.12 |
| SBP mmHg | 127.5 ± 8.3 | 133.8 ± 16.9 | 0.01 |
| DBP mmHg | 76.0 ± 7.2 | 80.4 ± 10.0 | 0.01 |
| SBP > 130 (median value) | 30 (35.7) | 27 (49.1) | 0.1 |
| SBP > 140 | 12 (14.3) | 13 (23.6) | 0.2 |
| Antihypertensive drugs | 44 (52.4) | 39 (70.9) | 0.03 |
| HDL mg/dl | 48.0 ± 11.8 | 49.5 ± 9.7 | 0.41 |
| Total cholesterol mg/dl | 180.2 ± 36.1 | 177.4 ± 32.7 | 0.6 |
| Smoking | 15 (19.7) | 11 (20.3) | 0.3 |
| Cigarette/diea | 17.8 ± 11.7 | 16.6 ± 13.4 | 0.99 |
| Atrial fibrillation | 1 (1.2) | 3(5.4) | 0.1 |
| FR Score (HVR) | 58(69.0) | 42 (75.4) | 0.3 |
| Myocardial infarction | 9 (11.0) | 6 (10.9) | 0.9 |
| Stroke | 0 | 1(1.8) | / |
| TIA | 0 | 0 | / |
| Average Wahlund | 2.2 ± 2.8 | 3.3 ± 4.5 | 0.07 |
| Wahlund score | |||
| 0 (score = 0) | 39 (46.4) | 26 (47.3) | |
| 1 (score 1–4) | 34(40.2) | 9 (16.4) | |
| 2 (score > 4) | 11 (13.1) | 20 (36.4) | |
Data presented are number (percentage %) for categorical and mean ± SD for continuous data. Significant results are expressed in bold
NC normal cognition, MCI mild cognitive impairment, H history, SBP systolic blood pressure, DBP diastolic blood pressure, HDL high density lipoproteins, FR score HVR Framingam Risk Score, high vascular risk, TIA transient ischemic attack
aNumber of cigarette/day was available for 126 subjects