Table 1.
Prestroke dependent (mRS 3–5) | Prestroke independent (mRS 0–2) | Dependent vs independent | |
---|---|---|---|
Value | Value | p value | |
Age, y, median (IQR) | 81 (73.75–85) | 72 (60–79) | < 0.0001 |
Female sex (%) | 52/84 (61.9) | 535/1163 (46.0) | 0.0063 |
Baseline NIHSS score, median (IQR) | 18 (11–21) | 15 (10–19) | 0.0113 |
Arterial hypertension (%) | 67/84 (79.8) | 784/1160 (67.6) | 0.0207 |
Diabetes mellitus (%) | 26/84 (31.0) | 185/1161 (15.9) | 0.0013 |
Hyperlipidemia (%) | 43/82 (52.4) | 661/1147 (57.6) | 0.3583 |
Smoking (%) | 9/64 (14.1) | 237/1063 (22.3) | 0.1595 |
Coronary Artery Disease (%) | 14/82 (17.1) | 217/1154 (18.8) | 0.771 |
History of previous stroke (%) | 27/82 (32.9) | 105/1158 (9.1) | < 0.0001 |
Pre-stroke use of antithrombotics (%) | 54/83 (65.1) | 491/1153 (42.6) | 0.0001 |
OTT [min], median (IQR) | 276.5 (199.5–352.25) | 272 (209–363) | 0.5836 |
Cause of stroke | 0.1325 | ||
Large artery atherosclerosis (%) | 5/84 (6) | 170/1163 (14.6) | |
Cardiac embolism (%) | 41/84 (48.8) | 485/1163 (41.7) | |
Small artery disease (%) | 0/84 (0) | 1/1163 (0.1) | |
Other determined cause (%) | 3/84 (3.6) | 69/1163 (5.9) | |
Undetermined cause (%) | 35/84 (41.7) | 438/1163 (37.7) |
IQR indicates Interquartile Range; NIHSS National Institutes of Health Stroke Scale; OTT onset to treatment time