Table 2.
Flow cytometry results the different subgroups of LE patients
| Parameters | Groups | IAB+ (n = 41) | AB− (n = 59) | F |
|---|---|---|---|---|
| HLADR+ CD4+ T cells CSF (cells/ml) | M/SD | 105.8 ± 232.7 | 90.8 ± 153.6 | 0.150 n.s |
| HLADR+ CD4+ T cells CSF %# | M/SD | 0.19 ± 0.13 | 0.16 ± 0.1 | 3.059 (*) |
| HLADR+ CD4+ T cells PB (cells/ml) | M/SD | 50,647 ± 111,55 | 48,073 ± 117,81 | 0.931 n.s |
| HLADR+ CD4+ T cells PB %# | M/SD | 0.09 ± 0.06 | 0.06 ± 0.05 | 9.858 ** |
| HLADR+ CD8+ T cells CSF (cells/ml) | M/SD | 47.1 ± 81.2 | 57.8 ± 70.4 | 0.484 n.s |
| HLADR+ CD8+ T cells CSF %# | M/SD | 0.53 ± 0.18 | 0.51 ± 0.19 | 0.266 n.s |
| HLADR+ CD8+ T cells PB (cells/ml) | M/SD | 32,77 ± 38,25 | 42,49 ± 86,80 | 0.442 n.s |
| HLADR+ CD8+ T cells PB %# | M/SD | 0.25 ± 0.20 | 0.16 ± 0.15 | 6.782 * |
| CD19+ B Cells CSF (cells/ml) | M/SD | 40.8 ± 214.9 | 6.04 ± 9.66 | 1.541 n.s |
| CD19+ B Cells PB (cells/ml) | M/SD | 140,54 ± 282,59 | 207.29 ± 458,00 | 0.674 n.s |
M mean, SD standard deviation, n number, IAB+ intracellular auto-antibody positive, AB− auto-antibodies negative
#Corresponds to the following formula: x% = absolute numbers of HLADR+ CD4+ T-cells or HLADR+ CD8+ T-cells in PB or CSF (cells/ml) divided by absolute number CD4+ T-cells or CD8+ T-cells in PB or CSF (cells/ml)
n.s. not significant; (*)p < 0.1, *p < 0.05, **p < 0.01 ANOVA (F statistics) with post hoc analysis (LSD) or frequency tabulation with Chi2 test