. 2020 Aug 20;268(2):455–466. doi: 10.1007/s00415-020-10158-1

Table 4.

Hierarchical regression models to predict cognitive performance in auto-antibody negative LE susceptive patients (AB−)

Cognitive functions	Predictors	β weights	T/significance
Verbal learning and memory (VLMT)
Learning model: F = 15.238, p < 0.001, R² = 0.498	Education	0.528	5.010, p < 0.001
Learning model: F = 15.238, p < 0.001, R² = 0.498	Female sex	0.333	3.184, p < 0.01
Memory (delayed recall) model: F = 18.668, p < 0.001, R² = 0.443	Education	0.560	5.138, p < 0.001
	Female sex	0.370	3.395, p < 0.01
Memory loss (after delay) model: F = 7.968, p < 0.01, R² = 0.142	Education	0.377	2.823, p < 0.01
Recognition model: F = 12.830, p < 0.001, R² = 0.456	Education	0.523	4.801, p < 0.001
	Duration	0.279	2.493, p < 0.05
	Sex female	0.255	2.272, p < 0.05
Figural learning and memory (DCS-R)
Learning model: F = 14.039, p < 0.001, R² = 0.384	Education	0.567	4.828, p < 0.001
Learning model: F = 14.039, p < 0.001, R² = 0.384	CD19+ B-cells in CSF	− 0.303	− 2.792, p < 0.05
Learning capacity model: F = 14.554, p < 0.001, R² = 0.388	Education	0.569	4.909, p < 0.001
Learning capacity model: F = 14.554, p < 0.001, R² = 0.388	CD19+ B-cells in CSF	− 0.315	− 2.713, p < 0.01
Recognition model: F = 8.281, p = 0.001, R² = 0.265	Education	0.420	3.316, p < 0.01
Executive functions (EpiTrack)
Model: F = 6.824, p < 0.001, R² = 0.367	Education	0.436	3.555, p < 0.01
	HLADR+ CD4+ T-cells in CSF %	− 0.327	− 2.781, p < 0.01
	HLADR+ CD4+ T-cells in PB (cells/ml)	− 0.284	− 2.340, p < 0.05
	Age at onset	0.219	1.759, p < 0.1
Mood (BDI I)
Model: F = 8.21, p < 0.001, R² = 0.286	Zonisamide	0.368	3.155, p < 0.01
Model: F = 8.21, p < 0.001, R² = 0.286	Duration of epilepsy	0.370	2.995, p < 0.01