Table 2.

ADRs and ADRs reported in ≥ 2  patients in any treatment group (extension study)

	Apararenone 2.5 mg N = 62	Apararenone 5 mg N = 64	Apararenone 10 mg N = 62
ADRs	3 (4.8)	8 (12.5)	3 (4.8)
Death	0	0	0
Serious ADRs	0	0	0
Patients who discontinued treatment because of an ADR	0	2 (3.1)	1 (1.6)
Hyperkalemia	0	0	0
Blood potassium increased	0	0	1 (1.6)
ADRs reported in ≥ 2 patients in any treatment group
Vascular disorders	0	3 (4.7)	0
Hypotension	0	2 (3.1)	0
Investigations	0	3 (4.7)	0
Blood potassium increased	0	2 (3.1)	0

Data are reported as n (%)

ADR adverse drug reaction