Table 4.
Pairwise comparison with Wilcoxon test after positive Friedman’s ANOVA test; for each tested variable (left column), the other variables from which (right column) it significantly differed are reported
| Variables | Mean rank | Significant differences (p < 0.05) |
|---|---|---|
| (1) Reference standard imaging | 2.82 | NCCT at baseline, CBV (colour-coded CT Perfusion 4D), CBF (colour-coded CT Perfusion 4D), CBF1 (colour-coded rapid) |
| (2) NCCT at baseline | 6.08 | All other variables |
| (3) MTT (colour-coded CT perfusion 4D) | 2.80 | NCCT at baseline, CBV (colour-coded CT perfusion 4D), CBF (colour-coded CT perfusion 4D), CBF1 (colour-coded rapid) |
| (4) CBV (colour-coded CT perfusion 4D) | 5.14 | Reference standard imaging, NCCT at baseline, MTT (colour-coded CT perfusion 4D), CBF (colour-coded CT perfusion 4D), Tmax1 (colour-coded rapid) |
| (5) CBF (colour-coded CT perfusion 4D) | 3.80 | All other variables |
| (6) Tmax1 (colour-coded rapid) | 2.48 | NCCT at baseline, CBV (colour-coded CT Perfusion 4D), CBF (colour-coded CT Perfusion 4D), CBF1 (colour-coded rapid) |
| (7) CBF1 (colour-coded rapid) | 4.90 | Reference standard imaging, NCCT at baseline, MTT (colour-coded CT perfusion 4D), CBF (colour-coded CT perfusion 4D), Tmax1 (colour-coded rapid) |
Furthermore, ASPECTSs assessed by qualitative evaluations were compared with the final score assigned by the reference standard imaging (control NCCT or MRI), distinguishing if the qualitative score was equal, higher and lower than the reference standard one. The comparison is resumed in Table 5.
Baseline NCCT showed significant most frequent higher values (84%, p < 0.05) and less frequent equal values (16%, p < 0.05). MTT (colour-coded CT perfusion 4D) and Tmax1 (colour-coded rapid) were the parameters with significant less frequent higher values (24%, p < 0.05; 22%, p < 0.05, respectively) and more frequent lower values (32%, and 38% p < 0.05, respectively) in comparison with the others; MTT (colour-coded CTP4D) and Tmax1 (colour-coded rapid) parameters resulted statistically equivalent to individualise perfusion changes.