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. 2020 Oct 1;31(3):1738–1747. doi: 10.1007/s00330-020-07297-4

Table 3.

Results of the log-rank test of the Kaplan-Meier analysis for NCT03439332 cohort: (1) all, (2) moderate vascular (rCBVHAT < rCBVth), and (3) high vascular (rCBVHAT > rCBVth). For each subpopulation, the mean OS and number of patients with methylated MGMT and unmethylated MGMT are presented. Additionally, differences between OS (days), hazard ratios, area under the curve (AUC), and log-rank test resulting p value are presented

No. of patients Median OS
Meth. MGMT Unmeth. MGMT Meth. MGMT Unmeth. MGMT ΔOS HR [95% CI] p AUC
All 43 53 507 373 134 2.10 [1.33–3.33] 0.0016 0.61
Moderate rCBV 19 29 678 411 267 2.73 [1.40–5.32] 0.0031 0.70
High rCBV 24 24 444 338 106 1.72 [0.90–3.27] 0.10 0.56