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. 2021 Feb 12;11:3715. doi: 10.1038/s41598-020-80641-2

Table 3.

Unadjusted hazard ratio and adjusted hazard ratio for all-cause mortality.

Unadjusted Adjusted
HR 95% CI P-value HR 95% CI P-value
Low MELD-XI score + high grip strength 1.00 [Reference] 1.00 [Reference]
Low MELD-XI score + low grip strength 3.18 1.65–6.13  < 0.001 2.02 1.02–3.98 0.042
High MELD-XI score + high grip strength 3.41 1.82–6.41  < 0.001 2.86 1.50–5.50 0.001
High MELD-XI score + low grip strength 6.59 3.66–11.88  < 0.001 3.80 2.04–7.08  < 0.001
Low MELD-XI score + high leg strength 1.00 [Reference] 1.00 [Reference]
Low MELD-XI score + low leg strength 3.79 1.94–7.39  < 0.001 3.36 1.69–6.65  < 0.001
High MELD-XI score + high leg strength 4.31 2.27–8.19  < 0.001 4.00 2.09–7.65  < 0.001
High MELD-XI score + low leg strength 6.49 3.54–11.92  < 0.001 4.65 2.47–8.75  < 0.001
Low MELD-XI score + high gait speed 1.00 [Reference] 1.00 [Reference]
Low MELD-XI score + low gait speed 1.77 0.94–3.33 0.075 1.13 0.59–2.18 0.708
High MELD-XI score + high gait speed 2.68 1.53–4.68  < 0.001 2.29 1.30–4.05 0.004
High MELD-XI score + low gait speed 4.25 2.54–7.09  < 0.001 2.49 1.43–4.33 0.001
Low MELD-XI score + high 6MWD 1.00 [Reference] 1.00 [Reference]
Low MELD-XI score + low 6MWD 5.12 2.62–10.01  < 0.001 3.93 1.95–7.94  < 0.001
High MELD-XI score + high 6MWD 4.07 2.11–7.82  < 0.001 3.79 1.95–7.37  < 0.001
High MELD-XI score + low 6MWD 7.93 4.33–14.52  < 0.001 5.48 2.88–10.41  < 0.001

Adjusted by age, sex, body mass index, B-Type natriuretic peptide, New York Heart Association classification, left ventricular ejection fraction, hypertension, dyslipidemia, diabetes mellitus, obesity and current smoking.

HR hazard ratio, CI confidence interval, MELD-XI score model for end stage liver disease excluding international normalized ratio score, 6MWD 6-min walking distance.