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. 2021 Feb 12;4:225. doi: 10.1038/s42003-021-01743-9

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© The Author(s) 2021, corrected publication 2021

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Fig. 2 — Location of Spike epitopes (SP1-SP11) is shown that in dark blue arrows. Primary structure domains are colored by green bars: SS, signal sequence; S2′, S2′ protease cleavage site; FP, fusion peptide; HR1, heptad repeat 1; CH, central helix; CD, connector domain; HR2, heptad repeat 2; TM, transmembrane domain; CT, cytoplasmic tail. “{” symbols indicate protease cleavage sites. Brown arrows denote ACE2-binding region and fusion peptide regions. *Epitopes with neutralizing antibody binding potential (SP1*, and SP9*).