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. Author manuscript; available in PMC: 2022 Sep 1.
Published in final edited form as: Biometrics. 2020 Aug 20;77(3):879–889. doi: 10.1111/biom.13351

TABLE 2.

Performance comparison between the single and multimodality methods Note. Reported are the estimation bias and mean squared error (MSE) of the total indirect effect, and the sensitivity and specificity, as well as the standard error (SE) of the measures, of the pathway selection

Scenario Method Bias MSE Sensitivity (SE) Specificity (SE)
(a) Multimodality 0.293 3.538 0.997 (0.035) 0.909 (0.030)
Single-modality 0.613 2.208 0.995 (0.050) 0.898 (0.044)
(b) Multimodality 0.069 23.95 0.966 (0.073) 0.935 (0.017)
Single-modality 0.306 22.91 0.998 (0.023) 0.929 (0.043)
(c-1) Multimodality 0.420 3.552 0.814 (0.151) 0.952 (0.011)
Single-modality 2.524 7.874 0.341 (0.302) 0.923 (0.045)
(c-2) Multimodality −0.015 14.55 0.814 (0.110) 0.958 (0.012)
Single-modality 1.219 13.23 0.638 (0.121) 0.982 (0.020)