Table 4.
Cumulative cure rates after multiple successive 131I radioiodine therapies
| Cumulative success after multiple RIT | High turnover (102)* | Normal turnover (208) | ||
|---|---|---|---|---|
| Cumulative frequency | Cumulative frequency | |||
| 1 RIT | 29 (28.4%) | 28.4% | 138(66.3%) | 66.3% |
| 2 RIT | 44 (43.1%) | 71.6% | 54(26%) | 92.3% |
| 3 RIT | 18 (17.6%) | 89.2% | 9 (4.3%) | 96.6% |
| ≥ 4 RIT | 11 (11.1%) | 100% | 7 (3.4%) | 100% |
| Median number of RIT required | 2 (1–5) | 1 (1–6) | (P 0.001) | |
| Median cumulative 131I activity required (mCi) | 15 (5–90) | 7 (5–100) | (P 0.001) | |
*2 patients, after they received their last RIT (which is after 12th month) did not follow up, hence could not be assessed for the final response (cured/not cured), but for treatment outcome at 12 months, they were taken as a failure for First RIT