Table 3.
Association between urinary propyl-paraben levels and EASI score in the total population as well as children with atopic dermatitis.
| Urinary propyl paraben levels | EASI score | |||||||
|---|---|---|---|---|---|---|---|---|
| All children | Children with atopic dermatitis symptoms in the previous 12 months | |||||||
| Crude OR (95% CI) | P value | aOR* (95% CI) | P value | Crude OR (95% CI) | P value | aOR* (95% CI) | P value | |
| 1st Quintile | Ref | – | Ref | – | Ref | – | Ref | – |
| 2nd Quintile | 1.701 (0.695–4.158) | 0.244 | 1.802 (0.726–0.473) | 0.204 | 1.684 (0.467–6.068) | 0.425 | 1.909 (0.506–7.196) | 0.340 |
| 3rd Quintile | 1.970 (0.821–4.726) | 0.129 | 1.863 (0.765–4.536) | 0.171 | 3.000 (0.812–11.081) | 0.099 | 3.112 (0.78812.290) | 0.105 |
| 4th Quintile | 1.402 (0.560–3.511) | 0.471 | 1.441 (0.570–3.640) | 0.440 | 1.429 (0.347–5.882) | 0.621 | 1.895 (0.428–8.392) | 0.400 |
| 5th Quintile | 2.247 (0.951–5.309) | 0.065 | 2.441 (1.014–5.876) | 0.046 | 3.500 (1.039–11.789) | 0.043 | 4.568 (1.215–17.172) | 0.025 |
aOR adjusted odds ratio, CI confidence interval, EASI Eczema Ares and Severity Index, Ref. reference population group.
*P values calculated by logistic regression analysis for positive EASI score.
Numbers in bold indicate a significant difference (P < .05).
*Logistic regression analysis was performed with an adjustment for confounding factors, including age, gender, body mass index z-score, the presence of visible mold at home, and exposure to environmental tobacco smoke.