Table 3.
Crude and adjusted hazard ratios (HR) for mortality by selected variables among HIV-infected participants of National NeuroAIDS Tissue Consortium (NNTC; n = 877).
| Variable (at baseline) | Crude HR (95% CI) | Adjusted HR (95% CI) modela |
|---|---|---|
| Global T scoreb | 0.99 (0.97–1.01) | NA |
| Age (years) | 1.01 (0.99–1.02) | NA |
| Gender | ||
| Female | Ref | NA |
| Male | 1.20 (0.90–1.61) | |
| Race | ||
| White | Ref | NA |
| Black | 1.15 (0.89–1.48) | |
| Other | 1.02 (0.63–1.66) | |
| Duration of HIV infection (years) | 1.02 (1.01–1.03) | 1.01 (0.99–1.03) |
| Ethnicity | ||
| Hispanic or Latino | Ref | Ref |
| Not Hispanic or Latino | 1.41 (1.05–1.88) | 1.38 (1.02–1.86) |
| ARV medication use | ||
| No current ARV use | Ref | NA |
| Current non-cART | 0.52 (0.32–0.86) | |
| Current cART | 0.53 (0.37–0.76) | |
| Serum hemoglobin (g/dl) | 0.89 (0.83–0.95) | 0.91 (0.85–0.97) |
| Plasma viral load (log10 copies/ml) | 1.28 (1.17–1.39) | 1.27 (1.16–1.39) |
| T scores × agec | ||
| 35 years | 1.13 (0.88–1.46) | 1.09 (0.85–1.41) |
| 55 years | 0.76 (0.61–9.95) | 0.79 (0.64–0.99) |
| 75 years | 0.51 (0.31–0.85) | 0.58 (0.35–0.97) |
aEach variable is adjusted for all other variables listed in the column.
bHazard Ratio corresponds to a 10-unit increase in global-t scores.
cInteraction term between global T scores and age. Hazard ratio corresponds to a 10-unit increase in global T scores for a given age.