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. 2021 Feb 12;11:3731. doi: 10.1038/s41598-021-82172-w

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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⁸⁹Zr-DFO-αGPC3 immuno-PET evaluates treatment response after ⁹⁰Y RIT. (a) Representative axial immuno-PET (left) and fused PET/CT (right) images from before (day 0) and 30 days after ⁹⁰Y-DOTA-αGPC3 RIT. Shaded PET area represents isocontour at 40% maximum signal intensity. (b) Serum AFP and GTV of same animal before (day 0) and 30 days after ⁹⁰Y-DOTA-αGPC3 RIT.