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. 2021 Feb 12;12:1008. doi: 10.1038/s41467-021-21182-8

Table 1.

Hepatocellular and cholangiocellular viability criteria for human donor livers during NMPa.

VITTAL criteria Groningen criteria
Hepatocellular criteria Hepatocellular criteria Cholangiocellular criteria
Lactate clearance Lactate clearance Delta bile pH
At least two of the following criteria Perfusate pH stabilization Delta bile bicarbonate
Bile production Delta bile glucose
- Bile production
- Perfusate pH stabilization
- Metabolism of glucose
- Stable flows
- Homogenous perfusion

aThe VITTAL criteria had to be met within 4 h of NMP, the Groningen criteria within 2.5 h of NMP1,8.