Subject	Health and medical sciences
Specific subject area	Vaccine surveillance studies, carriage survey
Type of data	Questionnaires, CSV files and data dictionary
How data were acquired	Data was collected by trained study personnel on a custom-built application for android phones. The questionnaires were designed in .xml format using Open Data Kit (ODK) software. Microbiological data was acquired by performing culture and sequential Multiplex PCR assay on the collected Nasopharyngeal swabs. Epidemiological data was then merged with the microbiological data using the common link ID (the study ID). Analysis and visualization were done using STATA version 15.0. and Microsoft Excel.
Data format	The uploaded files on Mendeley consist of 1.“Raw_dataset.csv” contains raw dataset in CSV format on epidemiological and microbiological fields on 3140 children under 2 years of age from a rural population in Pakistan. The data was collected between Oct 2014 to Sep 2018. 2.“Codebook.xls” describing individual fields in the dataset along with the codebook. 3.“DIB_questionaire.docx” is the field epidemiology questionnaire 4.“Lab_questionnaire.docx” is the Lab questionnaire
Parameters for data collection	Children under 2 years of age residing in two union councils (Khyber and Shah Alam Shah Jee Wasi) of Matiari, Sindh. Fifteen age-eligible children were enrolled every week from a continually updated line listing.
Description of data collection	Data was collected during household visits by trained study personnel. Data on socio-demographic and clinical characteristics was collected using questionnaires on smart phones whereas nasopharyngeal specimens were collected using standardised methods for further microbiological analysis.
Data source location	Institution: The Aga Khan University City: Karachi Country: Pakistan Latitude and longitude for collected samples/data: Matiari, Sindh, Pakistan, 25.680298, 68.502711
Data accessibility	The dataset can be accessed through the following link: Nisar, Muhammad Imran (2021), “Impact of PCV10 on nasopharyngeal carriage in children in Pakistan”, Mendeley Data, V1, doi:10.17632/t79h6g97gr.1
Related research article	[1] Nisar MI, Ahmed S, Jehan F, Shahid S, Shakoor S, Kabir F, Hotwani A, Munir S, Muhammad S, Khalid F, Althouse B, Hu H, Whitney C, Ali A, Zaidi AKM, Omer SB, Iqbal N. Direct and indirect effect of 10 valent pneumococcal vaccine on nasopharyngeal carriage in children under 2 years of age in Matiari, Pakistan. Vaccine. 2021 Jan 6:S0264-410X(20)31662-5. doi:10.1016/j.vaccine.2020.12.066. Epub ahead of print. PMID: 33422379.