Fig. 1.

Overview of MALDI-MSI data for a selection of 7 lipids. Data are shown for 6 tissue sections representative of the 106 section dataset, in terms of histological plaque composition. For comparison, histology segmentation images are also shown. The lipid images were normalized per m/z value, to enable reliable comparison of the distribution of a specific lipid in different tissue sections. Also, CE(18:2) and CE(18:1) are shown on the same intensity scale, as are DG and TG. Scale bars are 1 mm. CE, cholesterol ester; DG, diacylglycerol; FC, foam cells; LPC, lysophosphatidylcholines; NC, necrotic core; PC, phosphatidylcholines; SM, sphingomyelin; TG, triacylglycerol.