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. 2021 Jan 27;24(2):102093. doi: 10.1016/j.isci.2021.102093

Figure 9.

Figure 9

IL-27 signaling does not impact the survival of septic mice

(A) Wild-type (WT, dotted line) and Il27ra−/− (KO, solid line) mice underwent CLP and were followed for 7 days for survival. Each group contained 13 animals and was age and gender matched.

(B) Wild-type mice underwent CLP and received either saline (dotted line) or anti-IL-27 neutralizing mAb (solid line). Mice were followed for survival for 7 days following surgery. Each group contained 20 animals and was age and gender matched. All data shown are pooled from 2–3 independent experiments.