Table 3.
Accuracy of the Panbio™ test in patients tested 5 or fewer days (top) or more than 5 days (bottom) since symptom onset or close contact.
| Prevalence (%) | Sensitivity (%, 95% CI) | Specificity (%, 95% CI) | PPV (%, 95% CI) | NPV (%, 95% CI) | |
|---|---|---|---|---|---|
| ≤5 days | |||||
| Overall (N = 963) | 10.4% | 77.2% | 99.7% | 97.5% | 97.4% |
| 67.6%, 84.7% | 99.0%, 99.9% | 90.4%, 99.5% | 96.0%, 98.3% | ||
| Overall symptomatic (N = 556) | 12.7% | 83.1% | 99.5% | 96.7% | 97.5% |
| 71.9%, 90.5% | 98.3%, 99.9% | 87.6%, 99.4% | 95.6%, 98.6% | ||
| Overall asymptomatic (N = 407) | 7.3% | 63.3% | 100.0% | 100.0% | 97.1% |
| 43.9%, 79.4% | 99.0%, 100% | 82.3%, 100% | 94.8%, 98, 5% | ||
| GP referral for symptoms (N = 418) | 10.2% | 86.0% | 100.0% | 100.0% | 98.4% |
| 71.3%, 94.2% | 99.0%, 100% | 90.5%, 100% | 96.4%, 99.3% | ||
| Overall close contacts (N = 507) | 11.0% | 71.4% | 99.5% | 95.2% | 96.5% |
| 57.5%, 82.3% | 98.2%, 99.9% | 82.5%, 99.1% | 94.3%, 97.9% | ||
| Symptomatic close contacts (N = 117) | 23.0% | 77.7% | 97.7% | 91.3% | 93.6% |
| 57.2%, 90.6% | 91.4%, 99.6% | 70.4%, 98.4% | 86.0%, 97.3% | ||
| Asymptomatic close contacts (N = 390) | 7.4% | 65.5% | 100% | 100% | 97.3% |
| 45.6%, 82.0% | 98.9%, 100% | 82.3%, 100% | 95.0%, 98.7% | ||
| >5 days | |||||
| Overall (N = 213) | 8.9% | 73.6% | 100.0% | 100.0% | 97.4% |
| 48.5%, 89.8% | 98.1%, 100% | 76.8%, 100% | 93.9%, 99.0% | ||
| Overall symptomatic (N = 108) | 12.0% | 61.6% | 100.0% | 100% | 95% |
| 32.2%, 84.8% | 96.1%, 100% | 63.0%, 100% | 88.1%, 98.1% | ||
| Overall asymptomatic (N = 105) | 5.7% | 100.0% | 100.0% | 100.0% | 100.0% |
| 54.0%, 100% | 96.3%, 100% | 54.0%, 100% | 96.3%, 100% | ||
| GP referral for symptoms (N = 75) | 13.3% | 50.0% | 100.0% | 100.0% | 92.8% |
| 20.1%, 79.8% | 94.4%, 100% | 47.8%, 100% | 83.4%, 97, 3% | ||
| Overall close contacts (N = 135) | 6.7% | 100.0% | 100.0% | 100.0% | 100.0% |
| 66.3%, 100% | 97.1%, 100% | 66.3%, 100% | 97.1%, 100% | ||
| Symptomatic close contacts (N = 30) | 10.0% | 100.0% | 100.0% | 100.0% | 100.0% |
| 29.2%, 100% | 87.2%, 100% | 29.2%, 100% | 87.2%, 100% | ||
| Asymptomatic close contacts (N = 105) | 5.7% | 100.0% | 100.0% | 100.0% | 100.0% |
| 54.0%, 100% | 96.3%, 100% | 54.0%, 100% | 96.3%, 100% | ||
GP: general practitioner, 95%CI: 95% confidence interval, RT-PCR: Reverse-Transcription Polymerase Chain Reaction, Ag-RDT: rapid antigen diagnostic test.