Table 2.
List of the 8 clusters of biological processes is presented. The bold term is the name of cluster and Gog, and %AG and Nr.G refer to gene ontology group and numbers of gene, respectively. Gene ontology (GO) term p-value, term p-value corrected with Bonferroni step down, group p-value, and group p-value corrected with Bonferroni step down <0.05 were considered
| R | GOTerm | GOg | % A G | Nr. G | Associated Genes Found |
|---|---|---|---|---|---|
| 1 | response to cadmium ion | 1 | 4.55 | 3 | [B2M, HMOX1, SLC30A1] |
| 2 | cell-cell recognition | 2 | 4.11 | 3 | [B4GALT1, DLG1, LY6K] |
| 3 | positive regulation of protein targeting to mitochondrion | 3 | 4.30 | 4 | [MAGI1, NRG1, U2AF1, UBE2D3] |
| 4 | central nervous system neuron development | 4 | 4.05 | 3 | [NFIB, PTK2, ROBO1] |
| 5 | lamellipodium assembly | 5 | 4.76 | 3 | [ARHGEF7, NRG1, SRGAP2] |
| 6 | cellular response to vascular endothelial growth factor stimulus | 5 | 6.25 | 3 | [DLL4, NRG1, ROBO1] |
| 7 | neuron fate commitment | 5 | 5.80 | 4 | [DLL4, DLX2, ID2, NRG1] |
| 8 | forebrain cell migration | 5 | 5.97 | 4 | [EFHC1, NRG1, ROBO1, SRGAP2] |
| 9 | telencephalon cell migration | 5 | 6.25 | 4 | [EFHC1, NRG1, ROBO1, SRGAP2] |
| 10 | cerebral cortex cell migration | 5 | 6.12 | 3 | [EFHC1, ROBO1, SRGAP2] |
| 11 | cell-substrate junction assembly | 6 | 4.08 | 4 | [ARHGEF7, NRG1, PHLDB2, PTK2] |
| 12 | adherens junction assembly | 6 | 4.44 | 4 | [ARHGEF7, NRG1, PHLDB2, PTK2] |
| 13 | lamellipodium assembly | 6 | 4.76 | 3 | [ARHGEF7, NRG1, SRGAP2] |
| 14 | cell-substrate adherens junction assembly | 6 | 5.00 | 4 | [ARHGEF7, NRG1, PHLDB2, PTK2] |
| 15 | forebrain cell migration | 6 | 5.97 | 4 | [EFHC1, NRG1, ROBO1, SRGAP2] |
| 16 | focal adhesion assembly | 6 | 5.00 | 4 | [ARHGEF7, NRG1, PHLDB2, PTK2] |
| 17 | telencephalon cell migration | 6 | 6.25 | 4 | [EFHC1, NRG1, ROBO1, SRGAP2] |
| 18 | positive regulation of smooth muscle cell proliferation | 7 | 5.26 | 4 | [HMOX1, ID2, JAK2, NAMPT] |
| 19 | muscle cell apoptotic process | 7 | 5.26 | 3 | [HMOX1, JAK2, NRG1] |
| 20 | negative regulation of DNA binding | 7 | 7.41 | 4 | [DDIT3, HMOX1, JAK2, NFIB] |
| 21 | regulation of muscle cell apoptotic process | 7 | 5.66 | 3 | [HMOX1, JAK2, NRG1] |
| 22 | mammary gland epithelium development | 7 | 4.23 | 3 | [ID2, JAK2, ROBO1] |
| 23 | negative regulation of muscle cell apoptotic process | 7 | 9.09 | 3 | [HMOX1, JAK2, NRG1] |
| 24 | positive regulation of phosphatidylinositol 3-kinase signaling | 7 | 4.23 | 3 | [JAK2, NRG1, PTK2] |
| 25 | cell adhesion mediated by integrin | 8 | 5.08 | 3 | [CYP1B1, NRG1, PTK2] |
| 26 | regulation of cell adhesion mediated by integrin | 8 | 7.32 | 3 | [CYP1B1, NRG1, PTK2] |
| 27 | cell-substrate junction assembly | 8 | 4.08 | 4 | [ARHGEF7, NRG1, PHLDB2, PTK2] |
| 28 | muscle cell apoptotic process | 8 | 5.26 | 3 | [HMOX1, JAK2, NRG1] |
| 29 | regulation of cell-substrate junction assembly | 8 | 4.92 | 3 | [NRG1, PHLDB2, PTK2] |
| 30 | regulation of adherens junction organization | 8 | 4.69 | 3 | [NRG1, PHLDB2, PTK2] |
| 31 | adherens junction assembly | 8 | 4.44 | 4 | [ARHGEF7, NRG1, PHLDB2, PTK2] |
| 32 | lamellipodium assembly | 8 | 4.76 | 3 | [ARHGEF7, NRG1, SRGAP2] |
| 33 | cell-substrate adherens junction assembly | 8 | 5.00 | 4 | [ARHGEF7, NRG1, PHLDB2, PTK2] |
| 34 | regulation of muscle cell apoptotic process | 8 | 5.66 | 3 | [HMOX1, JAK2, NRG1] |
| 35 | focal adhesion assembly | 8 | 5.00 | 4 | [ARHGEF7, NRG1, PHLDB2, PTK2] |
| 36 | negative regulation of muscle cell apoptotic process | 8 | 9.09 | 3 | [HMOX1, JAK2, NRG1] |
| 37 | regulation of focal adhesion assembly | 8 | 4.92 | 3 | [NRG1, PHLDB2, PTK2] |
| 38 | positive regulation of phosphatidylinositol 3-kinase signaling | 8 | 4.23 | 3 | [JAK2, NRG1, PTK2] |