Table 3.
GO functional enrichment analysis for differentially expressed proteins and PPI of differentially expressed proteins of decompensated HCV- cirrhosis
Differentially expressed proteins | GO term | Description | Genes | P-value |
---|---|---|---|---|
BP | Complement, classical activation pathway | C3,IGKC,IGHA1 | 2.4E-6 | |
CC | Blood micro particle | C3,IGKC,IGHA1,HP,A1BG,APOA4 | 3.0E-13 | |
MF | No GO term | --------- | ------- | |
PPI of differentially expressed proteins | GO term | Description | Genes | P-value |
BP | Reverse cholesterol transport | APOA1,APOA2,APOA4,APOC3,APOE,CLU,LCAT | 3.0E-13 | |
CC | Blood micro particle | A1BG, AGT, AHSG, APOA1, APOA2, APOA4, APOE, C3, CLU,CP,GC,HPX,KNG1,TF | 2.1E20 | |
MF | Cholesterol binding | APOA1,APOA2,APOA4, APOC3, APOE,TSPO | 2.5E-9 |