Table 3.
The biological terms and pathways concerning hubs, bottlenecks, and hub-bottleneck genes including IL-7, GATA3, TXN, ETS-1, CCR7, CD28, and CD5
| R | Goterm | gene name |
|---|---|---|
| 1 | response to nitric oxide | CCR7, TXN |
| 2 | positive regulation of pri-miRNA transcription by RNA polymerase II | ETS-1, GATA3 |
| 3 | T cell differentiation in thymus | CCR7, CD28, GATA3, IL-7 |
| 4 | inflammatory response to antigenic stimulus | CCR7, CD28, GATA3 |
| 5 | interleukin-4 production | CD28, GATA3 |
| 6 | acute inflammatory response to antigenic stimulus | CCR7, GATA3 |
| 7 | lymphocyte costimulation | CCR7, CD28, CD5 |
| 8 | regulation of inflammatory response to antigenic stimulus | CCR7, CD28 |
| 9 | regulation of interleukin-4 production | CD28, GATA3 |
| 10 | hypersensitivity | CCR7, GATA3 |
| 11 | positive regulation of inflammatory response to antigenic stimulus | CCR7, CD28 |
| 12 | positive regulation of interleukin-4 production | CD28, GATA3 |
| 13 | T cell costimulation | CCR7, CD28, CD5 |
| 14 | T cell selection | CCR7, CD28, GATA3 |
| 15 | negative T cell selection | CCR7, CD28 |
| 16 | thymic T cell selection | CCR7, CD28, GATA3 |
| 17 | Selective expression of chemokine receptors during T-cell polarization | CCR7, CD28 |
| 18 | negative thymic T cell selection | CCR7, CD28 |