Table 4:
Key studies for mechanical thrombectomy.
| Study/year | N | Follow-up (days) | Sub massive PE n(%) | Massive PE n(%) | Results | Complications |
|---|---|---|---|---|---|---|
| FLARE/ 2018[16] |
106 | 30 | 104 (100) | 0 (0) | RV/LV ratio 1.53 to 1.15 in 48 h (P<0.0001) | AE-3.8% 1% major hemorrhage 1 death from undiagnosed breast cancer |
| Wible et al./2019 | 46 | 30 | 38 (82) | 8 (18) | Average MPAP before 33.9±8.9 mm Hg; after, 27.0±9.0 mm Hg (P<0.001). 71% experienced reduction in O2 requirements | 1 hemoptysis 1 procedure related blood loss requiring blood transfusion |
| EXTRACT-PE/2020 | 119 | NA | 119 (100) | 0(0) | Reduction in RV/LV ratio: 1.47–1.04. (27.3%). Reduction in systolic PA Pressure: 49–44.5 (9.2%) | MAE 1.7% (2) |
| Yasin et al./2020 |
8 | 90 | 7 (90) | 1 (10) | Reduction in MPAP: 27.8–20.5 (26.3%) | No procedure related adverse events |
PA: Pulmonary arteries, MPAP: Mean pulmonary artery pressure, RV: Right ventricle, LV: Left ventricle, MAE: Major adverse events